A concise, evidence-based medical tool that saves you money


If I have nerve (neuropathic) pain, does taking antidepressants help with reducing pain?


MedHead Confidence Score: 4
Amount Saved: $50 medical research cost post


MedHead Message:

Although antidepressants don’t help reduce general low back pain, they do reduce specific nerve pain. This pain can come as a result of diabetes or pinched nerves in the spine. Both amitriptyline and Effexor (venlafaxine) did the best. Effexor (around $15 per month) has fewer side effects but costs a little more per month than amitriptyline ($4 per month) if you get the generic version.


1. Saarto T, Wiffen PJ. Antidepressants for neuropathic pain. Cochrane Database of Systematic Reviews 2007, Issue 4. Art. No.: CD005454. DOI: 10.1002/14651858.CD005454.pub2. 2. https://www.goodrx.com/effexor-xr 3. https://www.goodrx.com/amitriptyline


Become A MedHead Today!