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Does the herbal supplement Cissus Quadrangularis help speed recovery time and reduce pain if a I have broken (fractured) bone?


MedHead Confidence Score: 1
Amount Saved: $50 medical research post


MedHead Message:

I’m always trying to help people heal faster when they break a bone. Nutrition is first and foremost the important factor, eating fresh whole fruits and vegetables while greatly limiting high sugar foods. However, there are a few decent studies that reveal that taking Cissus Quadrangularis whole herb 500mg-600mg daily for 6-8 weeks may reduce healing time by 1-2 weeks with side effects comparable to a placebo. If you have a bone fracture, you may consider adding this supplement to your regimen. Keep in mind our very low med-o-meter score on quality of evidence, so don’t throw out your crutches just yet.


1. Singh N, Singh V, Singh RK, Pant AB, Pal US, Malkunje LR, Mehta G. Osteogenic potential of cissus qudrangularis assessed with osteopontin expression. Natl J Maxillofac Surg. 2013 Jan;4(1):52-6. doi: 10.4103/0975-5950.117884. PMID: 24163553; PMCID: PMC3800385.

2. Sawangjit R, Puttarak P, Saokaew S, Chaiyakunapruk N. Efficacy and Safety of Cissus quadrangularis L. in Clinical Use: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Phytother Res. 2017 Apr;31(4):555-567. doi: 10.1002/ptr.5783. Epub 2017 Feb 6. PMID: 28165166.


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