Med-O-Meter

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MedHead Message:

The data on this is all over the place. Interestingly, although a recent cochrane review on this revealed a 66% reduction in mortality, however it was determined to be not statistically significant. Other reviews have been more favorable. However, reaching statistical significance seems just out of reach for these studies. Ivermectin by perscription for human use is cheap and largely very safe in every study used. Why is it so vilified? Seriously?

References:

• 1. Popp M, Stegemann M, Metzendorf M-I, Gould S, Kranke P, Meybohm P, Skoetz N, Weibel S. Ivermectin for preventing and treating COVID‐19. Cochrane Database of Systematic Reviews 2021, Issue 7. Art. No.: CD015017. DOI: 10.1002/14651858.CD015017.pub2. Accessed 11 January 2022.
• 2. Kow CS, Merchant HA, Mustafa ZU, Hasan SS. The association between the use of ivermectin and mortality in patients with COVID-19: a meta-analysis. Pharmacol Rep. 2021 Oct;73(5):1473-1479. doi: 10.1007/s43440-021-00245-z. Epub 2021 Mar 29. PMID: 33779964; PMCID: PMC8005369.
• 3. Kory, Pierre MD1,*; Meduri, Gianfranco Umberto MD2; Varon, Joseph MD3; Iglesias, Jose DO4; Marik, Paul E. MD5 Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19, American Journal of Therapeutics: May/June 2021 – Volume 28 – Issue 3 – p e299-e318 doi: 10.1097/MJT.0000000000001377.
• 4. Bryant A, Lawrie TA, Fordham EJ. Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines. American Journal of Therapeutics, 28, e434-e460, July 2021. Am J Ther. 2021;28(5):e573-e576. Published 2021 Aug 27. doi:10.1097/MJT.0000000000001442
• 5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415515/pdf/ajt-28-e576.pdf. Accessed 1/13/2022.