A concise, evidence-based medical tool that saves you money


Does taking a combination of Coenzyme Q10, Feverfew, and Magnesium help reduce and prevent my migraine headaches?


MedHead Confidence Score: 2
Amount Saved: $181 average cost of days work lost to migraine headache post


MedHead Message:

This is a mixed bag, likely due to problems getting decent clinical trials on natural products. However, the weight of the evidence shows that this combination probably works to reduce number of migraine days and overall pain levels. I recommend Magnesium oxide or chelate 500mg daily, with Coenzyme Q10 600mg daily, and Riboflavin (vitamin B2) 400mg daily for prevention. You may consider Feverfew 100 mg daily. It may take 1-2 months to start noticing improvement in headache symptoms.


1. Guilbot, A. et al. A combination of coenzyme Q10, feverfew and magnesium for migraine prophylaxis: a prospective observational study. BMC Complement Altern Med. 2017 Aug 30;17(1):433. doi: 10.1186/s12906-017-1933-7. 2. Maizels, M. et al. A Combination of Riboflavin, Magnesium, and Feverfew for Migraine Prophylaxis: A Randomized Trial. Headache: The Journal of Head and Face Pain, 44: 885-890. doi:10.1111/j.1526-4610.2004.04170.x


Become A MedHead Today!