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Does sublingual immunotherapy (drops under the tongue) work just as well as subcutaneous immunotherapy (allergy shots) for treating my chronic allergic rhinitis?


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MedHead Message:

Multiple lines of evidence all agree that immunotherapy drops under the tongue work at least as well as shots, are much more convenient because they can be taken at home. I would recommend it over injections due to cost savings and convenience.


1. Radulovic S, et al. Systematic reviews of sublingual immunotherapy (SLIT). Allergy2011;66: 740–752.

2. Radulovic S, Calderon MA, Wilson D, Durham S. Sublingual immunotherapy for allergic rhinitis. Cochrane Database of Systematic Reviews 2010, Issue 12. Art. No.: CD002893. DOI: 10.1002/14651858.CD002893.pub2.


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