A concise, evidence-based medical tool that saves you money


Does phentermine/topiramate combination cause me to have more weight loss than Xenical or Alli (orlistat)?


MedHead Confidence Score: 7
Amount Saved: $590 per month savings for Xenical v. generic phentermine and topiramate post


MedHead Message:

Phentermine is generic at around $10 per month. Topiramate is about $6 per month. Besides that, the generic phentermine with generic topiramate is actually MORE effective than the $607 per month alternative! Just think of all the money you are saving. Maybe you could spend it on buying smaller clothes.


1. Nuffer, W. et. al. A Comparison of New Pharmacological Agents for the Treatment of Obesity. Ann Pharmacother. 2016 May;50(5):376-88. doi: 10.1177/1060028016634351. Epub 2016 Feb 17. 2. Bays, H. Phentermine, topiramate and their combination for the treatment of adiposopathy (‘sick fat’) and metabolic disease.Expert Rev Cardiovasc Ther. 2010 Dec;8(12):1777-801. doi: 10.1586/erc.10.125. Epub 2010 Aug 16. 3. Garvey, T W, et. al. 3. Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study 4. www.goodrx.com/xenical?dosage=120mg&form=capsule&label_override=Xenical&quantity=90 4. www.goodrx.com/phentermine 5. www.goodrx.com/topiramate


Become A MedHead Today!