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Does magnesium reduce night time leg cramps in adults better than placebo?
MedHead Confidence Score: 9
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Wow. After years of actively prescribing magnesium for leg cramps, with outstanding success, I couldn’t find any studies to confirm this in large trials. I think we need to keep digging on this one. Perhaps another trial using folks with a verifiable magnesium deficiency? Check serum magnesium levels on every subject in the end to develop a protocol for a minimal magnesium blood level?
JAMA Intern Med. 2017 May 1;177(5):617-623. doi: 10.1001/jamainternmed.2016.9261 Effect of Magnesium Oxide Supplementation on Nocturnal Leg Cramps Cochrane Database Syst Rev. 2012 Sep 12;(9):CD009402. doi: 10.1002/14651858.CD009402.pub2.
Magnesium for skeletal muscle cramps.