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Does generic Fosamax (alendronate) work just as well as Prolia (Denosumab)?


MedHead Confidence Score: 7
Amount Saved: $1,170 per month taking alendronate instead of Prolia post


MedHead Message:

Generic Fosamax is $6 per month, compared to Prolia, and they work the same.


1. Effects of denosumab on bone mineral density and bone turnover in postmenopausal women., J Clin Endocrinol Metab, 2008, vol. 93 (pg. 2149-57) 2.Denosumab for prevention of fractures in postmenopausal women with osteoporosis., N Engl J Med, 2009, vol. 361 (pg. 756-65

3.Health Technol Assess. 2005 Jun;9(22):1-160.
A systematic review and economic evaluation of alendronate, etidronate, risedronate, raloxifene and teriparatide for the prevention and treatment of postmenopausal osteoporosis

4. https://www.goodrx.com/prolia?drug-name=prolia

5. https://www.goodrx.com/fosamax?drug-name=fosamax


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