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Does diclofenac give me the best pain relief for my knee or hip arthritis compared to other NSAID medications such as ibuprofen or naproxen?


MedHead Confidence Score: 5
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MedHead Message:

Diclofenac relieves pain the best of the current non-steroidal anti-inflammatory (NSAID) medications. However, it comes with some risks such as affecting the stomach lining, kidney, and liver over long periods of time. However, you may consider taking the gel version; however, this is very expensive as it is still sold only as brand-name.


1. da Costa BR, Reichenbach S et. al. Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis. Lancet. 2017 Jul 8;390(10090):e21-e33


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